Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752095 | 0.98 | LMNA (0.37) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7758044 | 0.98 | LMNA (0.37) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7758079 | 0.92 | LMNA (0.39) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7756648 | 0.91 | LMNA (0.38) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7757948 | 0.91 | LMNA (0.38) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7754808 | 0.91 | LMNA (0.45) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7752106 | 0.91 | LMNA (0.45) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7758067 | 0.89 | LMNA (0.44) | LMNAHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9070541 | 0.89 | LMNA (0.44) | LMNAGPR84MAPTMEN1THRB | |
| SCHEMBL7755423 | 0.88 | ALDH1A1 (0.40) | LMNAALDH1A1CYP3A4PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764636-B1 | Thiopropionate synergists | GOODYEAR TIRE & RUBBER (US) | 2001-03-07 | — | — | EP | disclosed |
| US-5672730-A | OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0764636-A2 | Thiopropionate synergists | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1997-03-26 | — | — | EP | disclosed |