Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL11311996 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KCNH2KDM5APHF8KDM4C | |
| Nitric Acid SCHEMBL28881964 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KCNH2KDM5APHF8KDM4C | |
| Nitric Acid SCHEMBL10905038 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KCNH2KDM5APHF8KDM4C | |
| Nitric Acid SCHEMBL28881954 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KCNH2KDM5APHF8KDM4C | |
| Nitric Acid SCHEMBL4562004 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KCNH2KDM5APHF8KDM4C | |
| Hexadecane SCHEMBL380459 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CES2CES1 | |
| Dodecane SCHEMBL29645029 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CES2CES1 | |
| Octane SCHEMBL8954452 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CES2CES1 | |
| Octane SCHEMBL9793297 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CES2CES1 | |
| Nonane SCHEMBL27883833 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103004351-B | Fertilization method for controlling nitrate content of leafy vegetables | UNIV SOOCHOW | 2014-07-02 | — | — | CN | disclosed |
| CN-103004351-A | Fertilization method for controlling nitrate content of leafy vegetables | UNIV SOOCHOW | 2013-04-03 | — | — | CN | disclosed |
| EP-0755938-B1 | Ligated polyoxometalates and method for their synthesis | GOODRICH CO B F (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-0755938-A1 | Ligated polyoxometalates and method for their synthesis | THE B.F. GOODRICH COMPANY (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5585510-A | COMPLEXES; IMPROVED SOLUBILITY IN ORGANIC SOLVENTS | THE B. F. GOODRICH COMPANY (US) | 1996-12-17 | — | — | US | disclosed |