Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL1832473 | 0.91 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL28881964 | 0.91 | ALDH1A1 (0.48) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL28881954 | 0.91 | ALDH1A1 (0.48) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL7752143 | 0.91 | ALDH1A1 (0.48) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL10905038 | 0.91 | ALDH1A1 (0.48) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL11311996 | 0.91 | ALDH1A1 (0.48) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL29142704 | 0.84 | ALOX15 (0.41) | ALDH1A1CA12CA1CA9KDM5A | |
| Nitric Acid SCHEMBL5875019 | 0.84 | CA5A (0.44) | ALDH1A1CA12CA1CA9CA5A | |
| Pentane SCHEMBL7754125 | 0.81 | — | — | |
| Hexane SCHEMBL27687689 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CA5ACA5BCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114790135-B | Preparation method of benzoyl formic acid | 浙江理工大学 | 2023-12-19 | — | — | CN | claimed |
| CN-114790135-A | Preparation method of benzoylformic acid | 浙江理工大学 | 2022-07-26 | — | — | CN | claimed |
| CN-113528218-A | Lubricant composition and friction coefficient control method | 清华大学 | 2021-10-22 | — | — | CN | claimed |
| CN-114790135-B | Preparation method of benzoyl formic acid | 浙江理工大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-114790135-A | Preparation method of benzoylformic acid | 浙江理工大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-108715590-B | Thiazolecarboxamide and picolinamide compounds useful as PIM kinase inhibitors | 因赛特公司 | 2022-03-08 | — | — | CN | disclosed |
| CN-113528218-A | Lubricant composition and friction coefficient control method | 清华大学 | 2021-10-22 | — | — | CN | disclosed |
| EP-2638115-B1 | METHOD OF PRINTING ON A FILM SUBSTRATE | VIDEOJET TECHNOLOGIES INC (US) | 2020-12-23 | — | — | EP | disclosed |
| US-8974050-B2 | Method of printing on a film substrate | VIDEOJET TECHNOLOGIES INC. (US) | 2015-03-10 | — | — | US | disclosed |
| EP-2638115-A1 | METHOD OF PRINTING ON A FILM SUBSTRATE | Videojet Technologies Inc. (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20130189503-A1 | METHOD OF PRINTING ON A FILM SUBSTRATE | VIDEOJET TECHNOLOGIES INC. (US) | 2013-07-25 | — | — | US | disclosed |
| WO-2012064796-A1 | METHOD OF PRINTING ON A FILM SUBSTRATE | VIDEOJET TECHNOLOGIES INC. (US) | 2012-05-18 | — | — | WO | disclosed |
| US-20080223785-A1 | Ionic Polymer Membranes | MILLER JEFFREY T | 2008-09-18 | — | — | US | disclosed |
| CN-101010130-A | Ionic polymer membranes | BP CORP NORTH AMERICA INC (US) | 2007-08-01 | — | — | CN | disclosed |
| EP-1784250-A2 | IONIC POLYMER MEMBRANES | BP Corporation North America Inc. (US) | 2007-05-16 | — | — | EP | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| WO-2006028529-A2 | IONIC POLYMER MEMBRANES | BP CORPORATION NORTH AMERICA INC. (US) | 2006-03-16 | — | — | WO | disclosed |
| US-20060049102-A1 | Ionic polymer membranes | BP CORPORATION NORTH AMERICA INC. | 2006-03-09 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4732705-A | ION EXCHANGE RESIN SOLIDIFIED WITH CEMENT | GESELLSCHAFT ZUR FORDERUNG DER INDUSTRIEORIENTIERTEN FORSCHUNG AN DEN SCHWEIZERISCHEN HOCHSCHULEN UND WEITEREN INSTITUTIONEN (CH) | 1988-03-22 | — | — | US | disclosed |