Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752155 | 0.91 | TDP1 (0.40) | MAPTTDP1CYP1A2PDK1HTT | |
| SCHEMBL7752158 | 0.78 | VCAM1 (0.32) | CYP1A2PDK1ALDH1A1TSHRVCAM1 | |
| SCHEMBL31094836 | 0.75 | TDP1 (0.41) | MAPTTDP1CYP1A2PDK1ALDH1A1 | |
| SCHEMBL4438662 | 0.74 | ATM (0.37) | MAPTTDP1CYP1A2HTTALDH1A1 | |
| SCHEMBL4438665 | 0.74 | ATM (0.37) | MAPTTDP1CYP1A2HTTALDH1A1 | |
| SCHEMBL31094807 | 0.73 | TDP1 (0.42) | MAPTTDP1TSHRVCAM1MAPK1 | |
| SCHEMBL31094884 | 0.70 | MAPT (0.41) | MAPTHTTALDH1A1GAA | |
| SCHEMBL7878524 | 0.69 | TSHR (0.52) | MAPTTDP1HTTALDH1A1TSHR | |
| SCHEMBL20942954 | 0.69 | TDP1 (0.47) | MAPTTDP1ALDH1A1TSHRHPGD | |
| SCHEMBL1343470 | 0.69 | CYP1A2 (0.44) | CYP1A2ALDH1A1TSHRCASP6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0610384-A4 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0610384-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009077-A2 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LABORATORIES (US) | 1993-05-13 | — | — | WO | disclosed |