Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | DTYMK | P23919 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752147 | 0.91 | MAPT (0.37) | TDP1CYP1A2MAPTTSHRCASP6 | |
| SCHEMBL31094836 | 0.76 | TDP1 (0.41) | TDP1CYP1A2MAPTTSHRPDK1 | |
| SCHEMBL7752161 | 0.75 | VCAM1 (0.35) | TDP1CYP1A2MAPTTSHRHTT | |
| SCHEMBL7752167 | 0.75 | VCAM1 (0.35) | TDP1CYP1A2MAPTTSHRHTT | |
| SCHEMBL7682006 | 0.74 | MAPK1 (0.49) | CYP1A2TSHRPDK1MAPK1VCAM1 | |
| SCHEMBL3866824 | 0.74 | ATM (0.53) | TDP1CYP1A2MAPTTSHRCASP6 | |
| SCHEMBL3528402 | 0.74 | ATM (0.49) | TDP1CYP1A2MAPTTSHRCASP6 | |
| SCHEMBL7057325 | 0.74 | ATM (0.53) | TDP1CYP1A2MAPTTSHRCASP6 | |
| SCHEMBL3528404 | 0.74 | ATM (0.49) | TDP1CYP1A2MAPTTSHRCASP6 | |
| SCHEMBL7682012 | 0.74 | MAPK1 (0.49) | CYP1A2TSHRPDK1MAPK1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0610384-A4 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0610384-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009077-A2 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LABORATORIES (US) | 1993-05-13 | — | — | WO | disclosed |