Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 5/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | CYP26A1 | O43174 | 8/20 | 0.47 |
| ▸ | CYP26B1 | Q9NR63 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | RARA | P10276 | 3/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.42 |
| ▸ | RARG | P13631 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CRABP2 | P29373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709238 | 0.82 | RXRA (0.49) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL3546404 | 0.76 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL2312146 | 0.76 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL14286073 | 0.76 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL1616186 | 0.76 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL12743622 | 0.76 | RXRA (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL7746459 | 0.74 | CYP26A1 (0.46) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL2897524 | 0.74 | CYP26B1 (0.53) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| Methyl Alcohol SCHEMBL7752255 | 0.73 | CYP26A1 (0.48) | RXRARXRBRXRGCYP26A1CYP26B1 | |
| SCHEMBL16998630 | 0.73 | CYP26B1 (0.51) | RXRARXRBRXRGCYP26A1CYP26B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832057-B1 | DIAROMATIC PROPYNYL OR DIENYL COMPOUNDS | CT INTERNAT DE (FR) | 2001-01-03 | — | — | EP | disclosed |