Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12054106 | 0.83 | CALM1 (0.48) | MAOBHSD17B2HTR1AALDH1A1CALM1 | |
| SCHEMBL13007829 | 0.82 | MAOB (0.50) | MAOBGAAKDM4EMAPTRAB9A | |
| SCHEMBL5885013 | 0.80 | BACE1 (0.50) | ESR1ESR2KDM4EMAPTGRM5 | |
| SCHEMBL29966495 | 0.80 | TDP1 (0.45) | MAPTMEN1KMT2A | |
| SCHEMBL156780 | 0.80 | TDP1 (0.45) | MAPTMEN1KMT2A | |
| SCHEMBL1745947 | 0.79 | CHRNB4 (0.45) | HSD17B2ALDH1A1 | |
| SCHEMBL4862178 | 0.79 | CYP11B2 (0.39) | — | |
| SCHEMBL6680825 | 0.79 | BRD4 (0.49) | NISCHESR1ESR2GAAKDM4E | |
| SCHEMBL14549021 | 0.78 | HSD17B2 (0.38) | MAOBHSD17B2HTR1AMEN1KMT2A | |
| SCHEMBL5209425 | 0.78 | CYP11B2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778262-B1 | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | CHEMAGIS LTD (IL) | 2001-01-24 | — | — | EP | claimed |
| US-5672755-A | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | CHEMAGIS LTD. (IL) | 1997-09-30 | — | — | US | claimed |
| EP-0778262-A2 | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | Chemagis Ltd. (IL) | 1997-06-11 | — | — | EP | claimed |
| US-11752103-B2 | Tramadol hydrochloride solution | ATHENA BIOSCIENCE, LLC (US) | 2023-09-12 | — | — | US | disclosed |
| US-20210299045-A1 | TRAMADOL HYDROCHLORIDE SOLUTION | ROSEMONT PHARMACEUTICALS LLC | 2021-09-30 | — | — | US | disclosed |
| US-20210137835-A1 | Tramadol Hydrochloride Solution | ROSEMONT PHARMACEUTICALS LLC | 2021-05-13 | — | — | US | disclosed |
| EP-0778262-B1 | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | CHEMAGIS LTD (IL) | 2001-01-24 | — | — | EP | disclosed |
| EP-0778262-A3 | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | Chemagis Ltd. (IL) | 1998-04-29 | — | — | EP | disclosed |
| US-5672755-A | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | CHEMAGIS LTD. (IL) | 1997-09-30 | — | — | US | disclosed |
| US-5672755-A | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | CHEMAGIS LTD. (IL) | 1997-09-30 | — | — | US | disclosed |
| EP-0778262-A2 | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | Chemagis Ltd. (IL) | 1997-06-11 | — | — | EP | disclosed |
| EP-0778262-A2 | Process for the purification of (RR-SS)-2-dimethyl-aminomethyl-1-(3-methoxyphenyl)cyclohexanol and its salts | Chemagis Ltd. (IL) | 1997-06-11 | — | — | EP | disclosed |