Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.54 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27033087 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL10791260 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL7595730 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL9436431 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL3960369 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL1500723 | 0.97 | LMNA (0.58) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL2786329 | 0.90 | LMNA (0.53) | TSHRLMNANFKB1PMP22GPR84 | |
| SCHEMBL27055258 | 0.88 | PPARG (0.63) | LMNAPPARGPPARDPPARAPTPN1 | |
| SCHEMBL27033221 | 0.88 | PPARG (0.63) | LMNAPPARGPPARDPPARAPTPN1 | |
| SCHEMBL21098894 | 0.86 | TSHR (0.44) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022075372-A1 | CARBOXYLIC ACID-COMODIFIED ORGANOPOLYSILOXANE AND USE THEREFOR | ダウ・東レ株式会社 | 2022-04-14 | — | — | WO | disclosed |
| US-9605113-B2 | Non-metal catalyzed room temperature moisture curable organopolysiloxane compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-20160130404-A1 | NON-METAL CATALYZED ROOM TEMPERATURE MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | MOMENTIVE PERFORMANCE MATERIALS INC. | 2016-05-12 | — | — | US | disclosed |
| EP-2994501-A2 | NON-METAL CATALYZED ROOM TEMPERATURE MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS | Momentive Performance Materials Inc. (US) | 2016-03-16 | — | — | EP | disclosed |
| US-20110182846-A1 | Surface Treating Agent, Surface-Treated Powder, And Cosmetic | SHISEIDO COMPANY LTD. (JP) | 2011-07-28 | — | — | US | disclosed |
| EP-1069129-A2 | Organofunctional cocyclic siloxanes | DOW CORNING CORPORATION (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6118014-A | Organofunctional cocyclic siloxanes | DOW CORNING CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |
| EP-0525479-B1 | Spicamycin derivatives and the use thereof | KIRIN BREWERY (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5631238-A | ANTICARCINOGENIC AGENTS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1997-05-20 | — | — | US | disclosed |
| US-5461036-A | Treating colon, gastric, esophageal cancer | KIRIN BEER KABUSHIKI KAISHA (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0525479-A1 | Spicamycin derivatives and the use thereof | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110182846-A1 | Surface Treating Agent, Surface-Treated Powder, And Cosmetic | CUTA, DSG1, TYR | TSHR 217/4885LMNA 3637/4885NFKB1 3674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.