SCHEMBL7752409

SCHEMBL7752409

O=S(=O)(c1ccc(OCc2ccccc2)cc1)c1ccccc1OCc1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.60
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
CA9 Q16790 2/20 0.60
CA4 P22748 1/20 0.60
CA5A P35218 1/20 0.60
CA7 P43166 1/20 0.60
CA5B Q9Y2D0 1/20 0.60
PTGES2 Q9H7Z7 1/20 0.53
AR P10275 9/20 0.52
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
NPC1 O15118 1/20 0.49
HPGD P15428 1/20 0.49
HTR6 P50406 1/20 0.49
LMNA P02545 1/20 0.49
CYP1A2 P05177 1/20 0.49
PTGS1 P23219 1/20 0.49
SLC6A2 P23975 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7751043 0.88 HTR6 (0.49) CA12CA1CA2CA9CA4
SCHEMBL7108877 0.85 MAPT (0.53) CA12CA1CA2CA9CA4
SCHEMBL7108878 0.85 CA12 (0.74) CA12CA1CA2CA9CA4
SCHEMBL7761854 0.85 CA12 (0.60) CA12CA1CA2CA9CA4
SCHEMBL9260073 0.84 CA12 (0.72) CA12CA1CA2CA9CA4
SCHEMBL28291811 0.84 CA12 (0.63) CA12CA1CA2CA9CA4
SCHEMBL1791781 0.83 HTR6 (0.46) SMN1; SMN2HPGDHTR6LMNACYP1A2
SCHEMBL5707066 0.83 CA12 (0.43) CA12CA1CA2CA9CA4
SCHEMBL419556 0.80 LMNA (0.73) CA12CA1CA2CA9CA4
SCHEMBL7830850 0.80 CA12 (0.66) CA12CA1CA2CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2001260540-A HEAT-SENSITIVE RECORDING MATERIAL NICCA CHEMICAL CO LTD 2001-09-25 JP disclosed