SCHEMBL7108877

SCHEMBL7108877

O=S(=O)(c1ccccc1OCc1ccccc1)c1ccccc1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
MAPK1 P28482 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
HTR1A P08908 2/20 0.50
ALPG P10696 1/20 0.50
PTK2B Q14289 1/20 0.50
DRD2 P14416 1/20 0.50
CCNB2 O95067 1/20 0.49
CDK1 P06493 1/20 0.49
CDK4 P11802 1/20 0.49
CCNB1 P14635 1/20 0.49
CCND1 P24385 1/20 0.49
CCNB3 Q8WWL7 1/20 0.49
LIPE Q05469 1/20 0.49
MGLL Q99685 1/20 0.48
LTA4H P09960 1/20 0.47
MAPK14 Q16539 1/20 0.47
BRD4 O60885 1/20 0.46
CA1 P00915 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745392 0.90 APP (0.47) MAPTL3MBTL1MAPK1TDP1HTR1A
SCHEMBL7751043 0.85 HTR6 (0.49) MAPTL3MBTL1MAPK1TDP1ALPG
SCHEMBL7752409 0.85 CA12 (0.60) MAPTL3MBTL1MGLLCA1CA2
SCHEMBL1013565 0.85 CA1 (0.56) MAPTL3MBTL1MAPK1TDP1HTR1A
SCHEMBL1028419 0.85 ALPG (0.51) MAPTL3MBTL1MAPK1TDP1HTR1A
SCHEMBL1500952 0.85 MAPT (0.50) MAPTL3MBTL1MAPK1TDP1HTR1A
SCHEMBL4164605 0.85 MAPT (0.55) MAPTL3MBTL1MAPK1TDP1HTR1A
SCHEMBL7267144 0.84 MAPT (0.49) MAPTL3MBTL1MAPK1TDP1HTR1A
SCHEMBL1791781 0.80 HTR6 (0.46) MAPTL3MBTL1TDP1HTR6SMN1; SMN2
SCHEMBL8369436 0.80 MAPT (0.49) MAPTL3MBTL1MAPK1TDP1HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed