Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.54 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.54 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.54 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.54 |
| ▸ | CETP | P11597 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776816 | 0.99 | EP300 (0.64) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL778783 | 0.99 | EP300 (0.64) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL776594 | 0.91 | KCNJ11 (0.63) | EP300RAB9AKCNJ11ABCC9ABCC8 | |
| SCHEMBL776746 | 0.88 | LMNA (0.60) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL774893 | 0.87 | NPC1 (0.59) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL776355 | 0.87 | NPC1 (0.59) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL30665215 | 0.86 | EP300 (0.65) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL31091435 | 0.84 | EP300 (0.66) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL8928921 | 0.83 | NPC1 (0.53) | EP300NPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL30665217 | 0.82 | EP300 (0.59) | EP300NPC1LMNARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |