Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | CETP | P11597 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776355 | 0.99 | NPC1 (0.59) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL774893 | 0.99 | NPC1 (0.59) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL778848 | 0.92 | MAPK1 (0.51) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL775262 | 0.88 | EP300 (0.61) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL776816 | 0.87 | EP300 (0.64) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL778783 | 0.87 | EP300 (0.64) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL9815030 | 0.84 | EP300 (0.60) | LMNASMN1; SMN2NPC1RAB9AEP300 | |
| SCHEMBL776464 | 0.80 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL776594 | 0.79 | KCNJ11 (0.63) | RAB9AEP300TSHRKDM4EALDH1A1 | |
| SCHEMBL30665215 | 0.77 | EP300 (0.65) | LMNASMN1; SMN2NPC1RAB9AEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8673998-B2 | Polymer compositions with improved cold flow | BRIDGESTONE CORPORATION (JP) | 2014-03-18 | — | — | US | disclosed |
| US-20120071583-A1 | POLYMER COMPOSITIONS WITH IMPROVED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2012-03-22 | — | — | US | disclosed |