SCHEMBL29376420

SCHEMBL29376420

C[C@@H](O)[C@H](NC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.50
▸ CASP3 P42574 4/20 0.46
▸ MDM4 O15151 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ EPHX2 P34913 1/20 0.43
▸ TLR2 O60603 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29603695 0.92 KMT2A (0.51) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL29697708 0.92 KMT2A (0.51) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL8902890 0.92 KMT2A (0.51) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL27637562 0.92 KMT2A (0.51) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL1486191 0.88 CASP3 (0.54) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL119400 0.88 CASP3 (0.54) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL31610887 0.88 CASP3 (0.54) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL29477078 0.88 CASP3 (0.54) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL2551441 0.88 CASP3 (0.54) KMT2ACASP3MDM4TP53EPHX2
SCHEMBL1486209 0.88 CASP3 (0.54) KMT2ACASP3MDM4TP53EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116948008-A Preparation method of salmon calcitonin 上海苏豪逸明制药有限公司 2023-10-27 — — CN claimed
US-20230220000-A1 PROCESS FOR PREPARING A GLP-1/GLUCAGON DUAL AGONIST ELI LILLY AND COMPANY 2023-07-13 — — US claimed
EP-4165058-A1 PROCESS FOR PREPARING A GLP-1/GLUCAGON DUAL AGONIST Eli Lilly and Company (US) 2023-04-19 — — EP claimed
US-20230047729-A1 METHOD FOR PREPARING LIRAGLUTIDE USING ENVIRONMENT-FRIENDLY SOLVENT DAEBONG LS CO., LTD. (KR) 2023-02-16 — — US claimed
EP-4116315-A1 METHOD FOR PREPARING LIRAGLUTIDE USING ENVIRONMENT-FRIENDLY SOLVENT Daebong LS Co., Ltd. (KR) 2023-01-11 — — EP claimed
CN-113501871-B Method for preparing darunavagon by combining solid phase with liquid phase 汉肽生物医药集团有限公司 2022-10-28 — — CN claimed
US-12630601-B2 Process for preparing a GIP/GLP1 dual agonist ELI LILLY AND COMPANY (US) 2026-05-19 — — US disclosed
US-12624079-B2 Process for preparing a GIP/GLP1 dual agonist ELI LILLY AND COMPANY (US) 2026-05-12 — — US disclosed
US-20260116848-A1 Synthesis of an Intermediate and Its Use for the Preparation of GLP-1R/GIPR Agonists CARMOT THERAPEUTICS INC. (US) 2026-04-30 — — US disclosed
US-20260035406-A1 SYNTHESIS OF GLP-1R/GIPR AGONISTS CARMOT THERAPEUTICS INC. (US) 2026-02-05 — — US disclosed
EP-4685157-A2 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Eli Lilly and Company (US) 2026-01-28 — — EP disclosed
EP-4685156-A2 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST Eli Lilly and Company (US) 2026-01-28 — — EP disclosed
US-20250382345-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST LILLY CO ELI (US) 2025-12-18 — — US disclosed
CN-113501871-B Method for preparing darunavagon by combining solid phase with liquid phase 汉肽生物医药集团有限公司 2022-10-28 — — CN disclosed
EP-3271398-B1 ANTI-MUC16 ANTIBODIES AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-31 — — EP disclosed
US-11396533-B2 Process for the manufacture of GLP-1 analogues Fresenius Kabi Ipsum S.R.L. (IT) 2022-07-26 — — US disclosed
CN-114573686-A Polypeptide containing disulfide bond and having serine protease activity inhibition function and application thereof 中国医学科学院药物研究所 2022-06-03 — — CN disclosed
CN-105017401-B Purification method of ziconotide 浙江和泽医药科技股份有限公司 2022-05-31 — — CN disclosed
US-20220135639-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST ELI LILLY AND COMPANY 2022-05-05 — — US disclosed
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES Fresenius Kabi Ipsum S.R.L. (IT) 2022-02-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116848-A1 Synthesis of an Intermediate and Its Use for the Preparation of GLP-1R/GIPR Agonists GLP1R, GIPR, CCKBR KMT2A 2588/4885CASP3 3659/4885MDM4 4227/4885
US-12624079-B2 Process for preparing a GIP/GLP1 dual agonist GLP1R, GIPR, GPR119 KMT2A 953/4885CASP3 4346/4885MDM4 4723/4885
US-12630601-B2 Process for preparing a GIP/GLP1 dual agonist GLP1R, GIPR, IAPP KMT2A 633/4885CASP3 4745/4885MDM4 4345/4885
US-20220041680-A1 PROCESS FOR THE MANUFACTURE OF GLP-1 ANALOGUES GLP1R, IAPP, VIP KMT2A 2915/4885CASP3 3093/4885MDM4 4464/4885
US-11396533-B2 Process for the manufacture of GLP-1 analogues GLP1R, IAPP, VIP KMT2A 2915/4885CASP3 3093/4885MDM4 4464/4885
US-20230220000-A1 PROCESS FOR PREPARING A GLP-1/GLUCAGON DUAL AGONIST GLP1R, GCGR, GCG KMT2A 2195/4885CASP3 2562/4885MDM4 4762/4885
US-20250382345-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST GLP1R, GIPR, GPR119 KMT2A 2749/4885CASP3 4305/4885MDM4 4854/4885
US-20220135639-A1 PROCESS FOR PREPARING A GIP/GLP1 DUAL AGONIST GLP1R, GIPR, GPR119 KMT2A 2749/4885CASP3 4305/4885MDM4 4854/4885
US-20260035406-A1 SYNTHESIS OF GLP-1R/GIPR AGONISTS GLP1R, GIPR, GRPR KMT2A 1129/4885CASP3 1940/4885MDM4 3842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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