SCHEMBL8731015

SCHEMBL8731015

C=CCCC[Si]1(c2ccccc2)CCC(=O)CC1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752946 0.86 POLB (0.31)
SCHEMBL8731527 0.78 MEN1 (0.30)
SCHEMBL8034665 0.78 CES2 (0.33)
SCHEMBL8077099 0.77 POLB (0.35) LMNA
SCHEMBL8021312 0.76 MEN1 (0.32)
SCHEMBL8456717 0.74
SCHEMBL8452872 0.74 ALDH1A1 (0.34) LMNA
SCHEMBL8916794 0.73 NPC1 (0.33)
SCHEMBL8454705 0.72 ALDH1A1 (0.33) LMNA
SCHEMBL7750933 0.72 ALDH1A1 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5730901-A Silacyclohexane compounds, preparation thereof liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-03-24 US disclosed
EP-0742222-A2 Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-11-13 EP disclosed