Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.61 |
| ▸ | MAOA | P21397 | 3/20 | 0.61 |
| ▸ | MIF | P14174 | 1/20 | 0.61 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | GLA | P06280 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA3 | P07451 | 2/20 | 0.58 |
| ▸ | CA4 | P22748 | 2/20 | 0.58 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132388 | 0.84 | MAOB (0.57) | MAOBMAOAMIFPFKFB3KDM4E | |
| SCHEMBL1406249 | 0.80 | KDM4E (0.76) | MAOBMAOAMIFPFKFB3KDM4E | |
| SCHEMBL7250759 | 0.79 | GPR35 (0.55) | MAOBMAOAKDM4EALDH1A1HPGD | |
| SCHEMBL25696561 | 0.78 | MAOB (0.67) | MAOBMAOAMIFPFKFB3KDM4E | |
| SCHEMBL8756161 | 0.77 | KDM4E (0.54) | MAOBMAOAMIFKDM4EGLA | |
| SCHEMBL25696493 | 0.77 | MAOB (0.67) | MAOBMAOAMIFPFKFB3KDM4E | |
| SCHEMBL12611191 | 0.77 | MIF (0.78) | MAOBMAOAMIFPFKFB3KDM4E | |
| SCHEMBL5595982 | 0.77 | L3MBTL1 (0.43) | MAOBMAOAKDM4EGLAALDH1A1 | |
| SCHEMBL30595106 | 0.77 | MAOB (0.78) | MAOBMAOAMIFPFKFB3KDM4E | |
| SCHEMBL11486663 | 0.77 | MAOB (0.78) | MAOBMAOAMIFPFKFB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769015-B1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5716944-A | USEFUL AS PROPHYLACTIC AND THERAPEUTIC AGENTS OF VARIOUS METABOLIC BONE DISEASES SUCH AS OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-10 | — | — | US | disclosed |
| EP-0769015-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996001267-A1 | PHOSPHONIC ACID COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-01-18 | — | — | WO | disclosed |