Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.76 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 8/20 | 0.66 |
| ▸ | MAOA | P21397 | 3/20 | 0.66 |
| ▸ | MIF | P14174 | 1/20 | 0.66 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.60 |
| ▸ | CA12 | O43570 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA4 | P22748 | 3/20 | 0.60 |
| ▸ | CA7 | P43166 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CA3 | P07451 | 2/20 | 0.60 |
| ▸ | CA6 | P23280 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.60 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967884 | 0.88 | KDM4E (0.67) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL25696561 | 0.88 | MAOB (0.67) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL6109767 | 0.87 | KDM4E (1.00) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL25203754 | 0.85 | MAOB (0.64) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL6111808 | 0.85 | MAOB (0.64) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL25697038 | 0.85 | MAOB (0.64) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL1406180 | 0.85 | MAOB (0.64) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL6478488 | 0.84 | MAOB (0.64) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL7752963 | 0.80 | MAOB (0.61) | KDM4ENOD2MAOBMAOAMIF | |
| SCHEMBL1406240 | 0.80 | MIF (1.00) | KDM4EMAOBMAOAMIFPFKFB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295053-B1 | Novel 2H-chromen-2-one-3-carboxamides for medical uses | INST MATERIA MEDICA CAMS (CN) | 2016-10-19 | — | — | EP | disclosed |
| US-8338401-B2 | Coumarin-amide derivatives and its preparation, said drug composition and its use | INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-12-25 | — | — | US | disclosed |
| US-8338401-B2 | Coumarin-amide derivatives and its preparation, said drug composition and its use | INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-12-25 | — | — | US | disclosed |
| US-8338401-B2 | Coumarin-amide derivatives and its preparation, said drug composition and its use | INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-12-25 | — | — | US | disclosed |
| EP-2295053-A1 | Novel 2H-chromen-2-one-3-carboxamides for medical uses | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2011-03-16 | — | — | EP | disclosed |
| US-20060148834-A1 | Novel coumarin-amide derivatives and its preparation, said drug composition and its use | INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2006-07-06 | — | — | US | disclosed |
| EP-1570846-A1 | THE NOVEL COUMARIN-AMIDE DERIVATIVES AND ITS PREPARATION, SAID DRUG COMPOSITION AND ITS USE | THE INSTITUTE OF MATERIA MEDICA OF CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2005-09-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148834-A1 | Novel coumarin-amide derivatives and its preparation, said drug composition and its use | INSR, GLS, INSRR | KDM4E 2436/4885NOD2 1597/4885MAOB 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.