SCHEMBL7753079

SCHEMBL7753079

CO/N=C(/C(=O)O)c1ccccc1COC/C=N/O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.45
HPGD P15428 1/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
TP53 P04637 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
CTBP2 P56545 1/20 0.31
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7752768 0.84 HIF1A (0.40) HIF1A
SCHEMBL25389981 0.81 HIF1A (0.52) HIF1AHPGDALDH1A1LMNATP53
SCHEMBL6156275 0.79 HIF1A (0.50) HIF1AALDH1A1LMNA
SCHEMBL6156279 0.79 HIF1A (0.50) HIF1AALDH1A1LMNA
SCHEMBL8210930 0.78 HIF1A (0.43) HIF1A
SCHEMBL8209643 0.78 HIF1A (0.43) HIF1A
SCHEMBL7751843 0.78 HIF1A (0.37) HIF1AHPGDALDH1A1HTTMAPT
SCHEMBL8623308 0.78 HIF1A (0.65) HIF1AALDH1A1TP53HTTKDM4E
SCHEMBL8623305 0.78 HIF1A (0.65) HIF1AALDH1A1TP53HTTKDM4E
SCHEMBL29037847 0.77 HIF1A (0.47) HIF1AHPGDALDH1A1LMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070052-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 2001-01-24 EP disclosed
WO-1999051579-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 1999-10-14 WO disclosed