SCHEMBL7752768

SCHEMBL7752768

CO/N=C(/C(=O)O)c1ccccc1COC/C=N/O[Si](C)(C)C(C)(C)C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.40
BACE1 P56817 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753079 0.84 HIF1A (0.45) HIF1A
SCHEMBL8210930 0.77 HIF1A (0.43) HIF1A
SCHEMBL7751843 0.77 HIF1A (0.37) HIF1A
SCHEMBL8209643 0.77 HIF1A (0.43) HIF1A
SCHEMBL7752188 0.76 HIF1A (0.39) HIF1A
SCHEMBL7751839 0.74 HIF1A (0.36) HIF1A
SCHEMBL6156275 0.73 HIF1A (0.50) HIF1A
SCHEMBL6156279 0.73 HIF1A (0.50) HIF1A
SCHEMBL25389981 0.73 HIF1A (0.52) HIF1A
SCHEMBL8214102 0.72 HIF1A (0.40) HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070052-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 2001-01-24 EP disclosed
WO-1999051579-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 1999-10-14 WO disclosed