SCHEMBL7751843

SCHEMBL7751843

CON=C(C(=O)O)c1ccccc1COCC=NOCc1ccc(Cl)s1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.37
ALDH1A1 P00352 4/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 4/20 0.32
KMT2A Q03164 4/20 0.32
MEN1 O00255 3/20 0.32
KDM4E B2RXH2 2/20 0.32
POLB P06746 1/20 0.32
HTT P42858 1/20 0.32
F2 P00734 2/20 0.31
HPGD P15428 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
F10 P00742 1/20 0.30
KLKB1 P03952 1/20 0.30
KLK1 P06870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7753079 0.78 HIF1A (0.45) HIF1AALDH1A1MAPTKDM4EHTT
SCHEMBL7751837 0.77 HIF1A (0.34) HIF1A
SCHEMBL7747803 0.77 HIF1A (0.34) HIF1A
SCHEMBL7752768 0.77 HIF1A (0.40) HIF1A
SCHEMBL7747800 0.75 ALDH1A1 (0.32) HIF1AALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL7751834 0.75 ALDH1A1 (0.32) HIF1AALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL7751839 0.73 HIF1A (0.36) HIF1AALDH1A1SMN1; SMN2MAPTKMT2A
SCHEMBL8209643 0.72 HIF1A (0.43) HIF1A
SCHEMBL8210930 0.72 HIF1A (0.43) HIF1A
SCHEMBL25389981 0.70 HIF1A (0.52) HIF1AALDH1A1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1070052-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 2001-01-24 EP disclosed
WO-1999051579-A1 FUNGICIDE COMPOSITIONS COMPRISING A HYDROXIMIC OR HYDRAZONIC GROUP AVENTIS CROPSCIENCE S.A. (FR) 1999-10-14 WO disclosed