SCHEMBL7753243

SCHEMBL7753243

Cc1ccc(S(=O)(=O)CCO)cc1N

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA2 P00918 8/20 0.55
ALDH1A1 P00352 5/20 0.49
HTT P42858 1/20 0.49
POLB P06746 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
MAPT P10636 2/20 0.42
LOX P28300 1/20 0.40
CYP3A4 P08684 2/20 0.40
TSHR P16473 1/20 0.40
CASP1 P29466 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
GAA P10253 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL130972 0.86 CA2 (0.53) CA2ALDH1A1HTTPOLBPTGDR2
SCHEMBL3369801 0.84 CA2 (0.60) CA2ALDH1A1HTTPOLBMAPT
SCHEMBL6936839 0.81 ALDH1A1 (0.44) CA2ALDH1A1HTTTDP1MAPT
SCHEMBL10606415 0.81 CA2 (0.81) CA2ALDH1A1POLBMAPTLOX
SCHEMBL5677264 0.81 CA2 (0.61) CA2ALDH1A1POLBMAPTLOX
SCHEMBL10725364 0.80 CA2 (0.51) CA2ALDH1A1HTTPOLBTDP1
SCHEMBL9404072 0.79 CA2 (0.55) CA2POLBMAPTLOXTSHR
SCHEMBL1371155 0.79 CA2 (0.53) CA2ALDH1A1HTTPOLBPTGDR2
SCHEMBL3423928 0.79 CA2 (0.59) CA2ALDH1A1HTTPOLBPTGDR2
SCHEMBL9338995 0.78 CA2 (0.67) CA2ALDH1A1POLBMAPTLOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1068390-A1 METHOD FOR IMPROVED WET STRENGTH PAPER Kimberly-Clark Worldwide, Inc. (US) 2001-01-17 EP disclosed
WO-1999045201-A1 METHOD FOR IMPROVED WET STRENGTH PAPER KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-09-10 WO disclosed
US-5935383-A Method for improved wet strength paper KIMBERLY-CLARK WORLDWIDE, INC. (US) 1999-08-10 US disclosed
EP-0387531-B1 PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES HOECHST AKTIENGESELLSCHAFT (DE) 1993-05-19 EP disclosed
EP-0384265-B1 PROCESS FOR THE PREPARATION OF BETA-CHLOROETHYL SULFONYL ARYL ISOCYANATES HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-31 EP disclosed
EP-0387531-A1 Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates HOECHST AKTIENGESELLSCHAFT (DE) 1990-09-19 EP disclosed
EP-0384265-A1 Process for the preparation of beta-chloroethyl sulfonyl aryl isocyanates HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
US-4948917-A REACTING PHOSGENE AND BETA-HYDROXYETHYLSULFONYL-ARYLAMINE HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-14 US disclosed
US-4745187-A Process for the preparation of water-soluble phthalocyanine dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1988-05-17 US disclosed
US-4237050-A Process for the preparation of water-soluble phthalocyanine dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1980-12-02 US disclosed
US-4229171-A Process for the preparation of fiber-reactive dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1980-10-21 US disclosed
US-4141890-A FIBER-REACTIVE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-RE29585-E DYEING WOOL CIBA-GEIGY CORPORATION (US) 1978-03-21 US disclosed
US-4067864-A FOR CELLULOSE OR POLYAMIDES CIBA-GEIGY AG (CH) 1978-01-10 US disclosed
US-4039523-A YELLOW CIBA-GEIGY AG (CH) 1977-08-02 US disclosed
US-4033980-A Phthalocyanine dyestuffs and process for preparing them HOECHST AKTIENGESELLSCHAFT (DT) 1977-07-05 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed
US-4001203-A Heavy metal complexes of azo dyestuffs containing a heterocyclic diazo component and the residue of 5-halogeno-2,3-dihydrozypyridine as coupling component CIBA-GEIGY AG (CH) 1977-01-04 US disclosed
US-3971738-A Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component CIBA-GEIGY AG (CH) 1976-07-27 US disclosed