⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907627 | 0.77 | — | — | |
| SCHEMBL6907919 | 0.77 | — | — | |
| SCHEMBL6504245 | 0.73 | — | — | |
| SCHEMBL3469258 | 0.70 | — | — | |
| SCHEMBL3093340 | 0.70 | — | — | |
| SCHEMBL28267609 | 0.69 | — | — | |
| SCHEMBL28929950 | 0.69 | — | — | |
| SCHEMBL28754485 | 0.67 | — | — | |
| SCHEMBL8164260 | 0.65 | — | — | |
| SCHEMBL3311966 | 0.64 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621060-A | MIXTURE OF POLYDIMETHYLSILOXANE END CAPPED WITH AMINO-ETHYL-AMINOPROPYLDIMETHYLSILANOL AND ORGANOTITANATE COMPOUND, APPLYING THE SELANT TO A SUBSTRATE, CURING THE PRIMER, APPLYING THIS ROOM TEMPERATURE VULCANIZABLE SELANT | GENERAL ELECTRIC COMPANY (US) | 1997-04-15 | — | — | US | claimed |
| EP-0731143-A2 | Solventless two component primer composition for improved adhesion of RTV silicone elastomers to substrates | GENERAL ELECTRIC COMPANY (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0731143-B1 | Solventless two component primer composition for improved adhesion of RTV silicone elastomers to substrates | GEN ELECTRIC (US) | 2001-01-17 | — | — | EP | disclosed |
| US-5621060-A | MIXTURE OF POLYDIMETHYLSILOXANE END CAPPED WITH AMINO-ETHYL-AMINOPROPYLDIMETHYLSILANOL AND ORGANOTITANATE COMPOUND, APPLYING THE SELANT TO A SUBSTRATE, CURING THE PRIMER, APPLYING THIS ROOM TEMPERATURE VULCANIZABLE SELANT | GENERAL ELECTRIC COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| EP-0731143-A2 | Solventless two component primer composition for improved adhesion of RTV silicone elastomers to substrates | GENERAL ELECTRIC COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5534610-A | Solventless two component primer composition for improved adhesion of RTV silicone elastomers to substrates | GENERAL ELECTRIC COMPANY (US) | 1996-07-09 | — | — | US | disclosed |