SCHEMBL7753555

SCHEMBL7753555

CCCN(Cc1ccc(Cl)nc1)/C(=C/[N+](=O)[O-])NC

nearest known ligand 0.83

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 2/20 0.36
CHRNA4 P43681 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 4/20 0.35
FAAH O00519 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
RXFP1 Q9HBX9 1/20 0.35
CHRNA1 P02708 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA7 P36544 1/20 0.35
CASP6 P55212 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7660190 1.00 CHRNB2 (0.36) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
Nitenpyram SCHEMBL29388004 0.91 SMN1; SMN2 (0.40) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
Nitenpyram SCHEMBL31030931 0.91 SMN1; SMN2 (0.40) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
Nitenpyram SCHEMBL25789 0.91 SMN1; SMN2 (0.40) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
Nitenpyram SCHEMBL25788 0.91 SMN1; SMN2 (0.40) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
Nitenpyram SCHEMBL13448342 0.91 SMN1; SMN2 (0.40) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
SCHEMBL8703934 0.90 CHRNB2 (0.36) CHRNB2CHRNA4SMN1; SMN2ALDH1A1CYP3A4
Nitenpyram SCHEMBL28400760 0.89 SMN1; SMN2 (0.39) CHRNB2CHRNA4SMN1; SMN2ALDH1A1FAAH
SCHEMBL7668848 0.89 CHRNB2 (0.38) CHRNB2CHRNA4SMN1; SMN2ALDH1A1CYP3A4
SCHEMBL7668662 0.85 ALDH1A1 (0.36) CHRNB2CHRNA4SMN1; SMN2ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0632957-B1 A method of killing noxious insects BAYER AGROCHEM KK (JP) 2001-01-17 EP disclosed
EP-0648412-B1 Poisonous baits for controlling soil-inhabiting pests BAYER AGROCHEM KK (JP) 1998-12-02 EP disclosed
US-5661164-A APPLYING A SYNERGISTIC MIXTURE OF CYFLUTHRIN, 1-(6-CHLORO-3-PYRIDYLMETHYL)-N-NITROIMIDAZOLIDIN-2-YLIDENE-AMINE AND A CARRIER NIHON BAYER AGROCHEM K.K. (JP) 1997-08-26 US disclosed
US-5561945-A PRESSURE FORCES ABSORPTION OF ACTIVE MATERIAL INTO STEMS NIHON BAYER AGROCHEM K.K. (JP) 1996-10-08 US disclosed
US-5455256-A Controlling thrips NIHON BAYER AGROCHEM K.K. (JP) 1995-10-03 US disclosed
EP-0648412-A1 Poisonous baits for controlling soil-inhabiting pests NIHON BAYER AGROCHEM K.K. (JP) 1995-04-19 EP disclosed
EP-0632957-A1 A method of killing noxious insects NIHON BAYER AGROCHEM K.K. (JP) 1995-01-11 EP disclosed
EP-0617890-A1 Synergistic insecticidal compositions NIHON BAYER AGROCHEM K.K. (JP) 1994-10-05 EP disclosed
US-5196442-A Chloropyridyl compounds NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1993-03-23 US disclosed
US-5087632-A Formicidal agent for combating termites NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1992-02-11 US disclosed