Nitenpyram

Nitenpyram

SCHEMBL13448342

CCN(Cc1ccc(Cl)nc1)/C(=C\[N+](=O)[O-])NC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
CHRNA1 P02708 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA7 P36544 1/20 0.38
CHRNB2 P17787 2/20 0.38
CHRNA4 P43681 2/20 0.38
CASP6 P55212 1/20 0.36
FAAH O00519 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitenpyram SCHEMBL25788 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
Nitenpyram SCHEMBL31030931 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
Nitenpyram SCHEMBL25789 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
Nitenpyram SCHEMBL29388004 1.00 SMN1; SMN2 (0.40) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
Nitenpyram SCHEMBL28400760 0.98 SMN1; SMN2 (0.39) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
Nitenpyram SCHEMBL20425327 0.91 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
SCHEMBL7660190 0.91 CHRNB2 (0.36) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
SCHEMBL7753555 0.91 CHRNB2 (0.36) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
SCHEMBL7668848 0.91 CHRNB2 (0.38) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6
SCHEMBL7678862 0.90 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1MAPTCYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010028012-A1 METHOD FOR CONTROLLING NEMATODE PESTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-11 WO disclosed
US-7271184-B2 Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides NOVARTIS ANIMAL HEALTH US, INC. (US) 2007-09-18 US disclosed
US-7271184-B2 Acyclic and cyclic guanidine- and acetamidine derivatives, their preparation and their use as pesticides, esp. as parasiticides NOVARTIS ANIMAL HEALTH US, INC. (US) 2007-09-18 US disclosed