SCHEMBL775357

SCHEMBL775357

O=C(O)c1ccc(-c2ccc(CCCS)s2)s1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.44
LMNA P02545 1/20 0.44
PRNP P04156 1/20 0.44
RECQL P46063 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
POLB P06746 2/20 0.44
MEN1 O00255 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
TDP1 Q9NUW8 2/20 0.42
DAO P14920 1/20 0.42
HPGD P15428 4/20 0.41
KDM4E B2RXH2 2/20 0.41
GAA P10253 1/20 0.41
HPGDS O60760 1/20 0.40
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
FAAH O00519 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776619 0.95 ALDH1A1 (0.47) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL774287 0.90 MEN1 (0.46) ALDH1A1POLBMEN1RAB9AKMT2A
SCHEMBL775264 0.83 MEN1 (0.49) ALDH1A1POLBMEN1RAB9AKMT2A
SCHEMBL10020293 0.81 MEN1 (0.47) ALDH1A1POLBMEN1RAB9AKMT2A
SCHEMBL7644385 0.79 DAO (0.50) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL593023 0.76 MEN1 (0.65) ALDH1A1POLBMEN1RAB9AKMT2A
SCHEMBL13891701 0.76 HPGD (0.49) ALDH1A1PRNPRXFP1POLBMEN1
SCHEMBL846642 0.75 POLB (0.56) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL9849708 0.75 ALDH1A1 (0.55) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL4197226 0.74 ALDH1A1 (0.51) ALDH1A1LMNAPRNPRECQLRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663451-B2 Linker, impedance biochip, and method of quantitatively detecting target analyte in fluid sample using the biochip NATIONAL TAIWAN UNIVERSITY (TW) 2014-03-04 US claimed
US-20120067742-A1 LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP NATIONAL TAIWAN UNIVERSITY (TW) 2012-03-22 US claimed
US-8663451-B2 Linker, impedance biochip, and method of quantitatively detecting target analyte in fluid sample using the biochip NATIONAL TAIWAN UNIVERSITY (TW) 2014-03-04 US disclosed
US-20120067742-A1 LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP NATIONAL TAIWAN UNIVERSITY (TW) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120067742-A1 LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP EPCAM, CA13, CD44 ALDH1A1 1831/4885LMNA 1192/4885PRNP 2950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.