Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.44 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500506 | 1.00 | MTNR1A (0.44) | MTNR1AMTNR1BACACBACACACYP1A2 | |
| SCHEMBL11384019 | 0.75 | MTNR1A (0.57) | MTNR1AMTNR1BACACBACACACYP1A2 | |
| SCHEMBL10600797 | 0.72 | CYP1A2 (0.39) | MTNR1AMTNR1BCYP1A2CYP2C19PPARA | |
| SCHEMBL5599032 | 0.71 | TDP1 (0.45) | TSHRMEN1ALDH1A1KMT2A | |
| SCHEMBL7855245 | 0.70 | MTNR1A (0.51) | MTNR1AMTNR1BACACBACACACYP1A2 | |
| SCHEMBL18342941 | 0.70 | MTNR1A (0.51) | MTNR1AMTNR1BACACBACACACYP1A2 | |
| SCHEMBL13536230 | 0.70 | CTRB1 (0.51) | MTNR1AMTNR1BMEN1ALDH1A1KMT2A | |
| SCHEMBL4243856 | 0.70 | CHRNB4 (0.49) | MTNR1AMTNR1BTSHR | |
| SCHEMBL11847238 | 0.68 | MTNR1A (0.49) | MTNR1AMTNR1BACACBACACAMEN1 | |
| SCHEMBL9587807 | 0.67 | TDP1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070046-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051564-A1 | PROPANOLAMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-14 | — | — | WO | disclosed |