Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 11/20 | 0.44 |
| ▸ | MMP13 | P45452 | 9/20 | 0.44 |
| ▸ | MMP9 | P14780 | 8/20 | 0.44 |
| ▸ | MMP1 | P03956 | 7/20 | 0.44 |
| ▸ | MMP3 | P08254 | 7/20 | 0.44 |
| ▸ | MMP8 | P22894 | 6/20 | 0.44 |
| ▸ | MMP7 | P09237 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752664 | 0.88 | SYK (0.47) | ALDH1A1HSD17B10MMP2MMP9LMNA | |
| SCHEMBL7753610 | 0.83 | ITGAV (0.57) | MMP7 | |
| SCHEMBL7400842 | 0.81 | SYK (0.46) | ALDH1A1HSD17B10HPGDMMP2MMP9 | |
| SCHEMBL7400840 | 0.81 | SYK (0.46) | ALDH1A1HSD17B10HPGDMMP2MMP9 | |
| SCHEMBL13639192 | 0.80 | MMP2 (0.50) | ALDH1A1HSD17B10HPGDMMP2MMP13 | |
| SCHEMBL13639249 | 0.80 | MMP2 (0.50) | ALDH1A1HSD17B10HPGDMMP2MMP13 | |
| SCHEMBL7753410 | 0.79 | STS (0.54) | ALDH1A1MMP2MMP13MMP9MMP1 | |
| SCHEMBL7752387 | 0.79 | MMP2 (0.44) | ALDH1A1HSD17B10MMP2MMP9MMP8 | |
| SCHEMBL16607500 | 0.79 | CA12 (0.50) | MMP2MMP13MMP3CA1CA2 | |
| SCHEMBL26464688 | 0.79 | CA12 (0.50) | MMP2MMP13MMP3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |