Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 8/20 | 0.44 |
| ▸ | MMP9 | P14780 | 8/20 | 0.44 |
| ▸ | MMP8 | P22894 | 5/20 | 0.44 |
| ▸ | MMP12 | P39900 | 5/20 | 0.44 |
| ▸ | MMP14 | P50281 | 5/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7752666 | 0.92 | MMP2 (0.45) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL7752664 | 0.91 | SYK (0.47) | MMP2MMP9ITGB3ITGA2BPSMB8 | |
| SCHEMBL7754751 | 0.87 | MMP2 (0.42) | MMP2MMP9MMP8MMP12MMP14 | |
| SCHEMBL7754665 | 0.87 | ITGB3 (0.46) | ITGB3ITGA2BPSMB8 | |
| SCHEMBL7753684 | 0.84 | MEN1 (0.41) | MMP2MMP9MMP8CA1CA2 | |
| SCHEMBL7752670 | 0.83 | ITGAV (0.42) | ITGB3ITGA2BCA1CA2ALDH1A1 | |
| SCHEMBL7753284 | 0.82 | MMP13 (0.47) | MMP2MMP9MMP8ALDH1A1 | |
| SCHEMBL7400842 | 0.82 | SYK (0.46) | MMP2MMP9ITGB3ITGA2BCA1 | |
| SCHEMBL7400840 | 0.82 | SYK (0.46) | MMP2MMP9ITGB3ITGA2BCA1 | |
| SCHEMBL7753201 | 0.81 | MMP13 (0.46) | MMP2MMP9MMP8ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |