Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | YWHAG | P61981 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460892 | 0.86 | KDM4E (0.57) | NR1H4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL7841921 | 0.81 | ALDH1A1 (0.53) | MAPTKDM4EALDH1A1GAAALOX15 | |
| SCHEMBL28388299 | 0.81 | PARP1 (0.41) | NR1H4KDM4EALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL3782361 | 0.81 | GAA (0.53) | MAPTKDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL28318361 | 0.79 | KDM4E (0.50) | NR1H4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL8976949 | 0.79 | CES2 (0.42) | KMT2AL3MBTL1PTGS2DGAT1 | |
| SCHEMBL28246644 | 0.78 | GAA (0.46) | NR1H4MAPTKDM4EALDH1A1GAA | |
| Cyclohexane SCHEMBL28715545 | 0.77 | GAA (0.48) | MAPTKDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL14948225 | 0.77 | ALDH1A1 (0.49) | MAPTKDM4EALDH1A1GAACYP3A4 | |
| SCHEMBL29004469 | 0.75 | L3MBTL1 (0.37) | NR1H4MAPTKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110305032-A | The preparation method of N- tert-butyl -4- aminobenzamide | 常州永和精细化学有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-110305032-A | The preparation method of N- tert-butyl -4- aminobenzamide | 常州永和精细化学有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110305032-A | The preparation method of N- tert-butyl -4- aminobenzamide | 常州永和精细化学有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110305032-A | The preparation method of N- tert-butyl -4- aminobenzamide | 常州永和精细化学有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110229113-A | A kind of preparation method of ultraviolet absorber HEB | 湖北师范大学 | 2019-09-13 | — | — | CN | disclosed |
| US-6271265-B1 | N-TERT-BUTYL-2-HYDROXYBENZAMIDE FOR INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. | 2001-08-07 | — | — | US | disclosed |
| EP-1077699-A1 | AMIDE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059582-A1 | AMIDE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |
| EP-0570838-B1 | s-Triazine derivatives as light stabilisers | 3V SIGMA SPA (IT) | 1999-08-11 | — | — | EP | disclosed |
| US-5346691-A | FOR USE IN DERMATOLOGICAL AND COSMETIC COMPOSITIONS | 3V INC. (US) | 1994-09-13 | — | — | US | disclosed |
| EP-0570838-A1 | S-triazine derivatives as light stabilisers | 3V SIGMA S.p.A (IT) | 1993-11-24 | — | — | EP | disclosed |