Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.49 |
| ▸ | ITGA5 | P08648 | 5/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.49 |
| ▸ | ITGAV | P06756 | 4/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.49 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.44 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | F13A1 | P00488 | 4/20 | 0.42 |
| ▸ | TGM2 | P21980 | 4/20 | 0.42 |
| ▸ | TGM1 | P22735 | 4/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27449333 | 0.92 | ITGB3 (0.56) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL7748735 | 0.92 | ITGB3 (0.56) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL27461971 | 0.82 | F13A1 (0.48) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL7753284 | 0.79 | MMP13 (0.47) | ALDH1A1MMP1MMP2MMP3MMP9 | |
| SCHEMBL7753201 | 0.78 | MMP13 (0.46) | ITGB3ITGA2BMMP1MMP2MMP3 | |
| SCHEMBL7394756 | 0.75 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7753699 | 0.74 | ITGB3 (0.54) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL27448890 | 0.74 | ITGB3 (0.54) | ITGB1ITGA5ITGB3ITGAVITGA2B | |
| SCHEMBL7752422 | 0.74 | ITGB3 (0.52) | ITGB3ITGA2B | |
| SCHEMBL6977329 | 0.73 | TGFBR1 (0.43) | ITGB3ITGA2BMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |