Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.73 |
| ▸ | DRD2 | P14416 | 1/20 | 0.73 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.73 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.73 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.73 |
| ▸ | HRH1 | P35367 | 1/20 | 0.73 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.73 |
| ▸ | HTR2B | P41595 | 1/20 | 0.73 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8637180 | 0.99 | LMNA (0.71) | LMNAHTTCHRM2ADORA3CHRM1 | |
| SCHEMBL7757458 | 0.93 | HTT (0.61) | LMNAHTTCHRM2ADORA3CHRM1 | |
| Hydrochloric Acid SCHEMBL8637261 | 0.92 | HTT (0.60) | LMNAHTTCHRM2ADORA3CHRM1 | |
| SCHEMBL7756379 | 0.88 | MEN1 (0.61) | LMNAHTTCHRM2ADORA3CHRM1 | |
| SCHEMBL1152274 | 0.87 | LMNA (0.91) | LMNAHTTCHRM2ADORA3CHRM1 | |
| Hydrochloric Acid SCHEMBL8637185 | 0.87 | MEN1 (0.60) | LMNAHTTCHRM2ADORA3CHRM1 | |
| Hydrochloric Acid SCHEMBL7324923 | 0.86 | LMNA (0.89) | LMNAHTTCHRM2ADORA3CHRM1 | |
| Fumaric Acid SCHEMBL7320343 | 0.86 | LMNA (0.77) | LMNAHTTCHRM2ADORA3CHRM1 | |
| Fumaric Acid SCHEMBL7320354 | 0.86 | LMNA (0.77) | LMNAHTTCHRM2ADORA3CHRM1 | |
| SCHEMBL7757934 | 0.85 | ALDH1A1 (0.56) | LMNAHTTCHRM2ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0847999-B1 | N-benzylpiperazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-21 | — | — | EP | disclosed |