Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.32 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753761 | 1.00 | KMT2A (0.41) | KMT2AP2RX7RAB9ANPC1ALDH1A1 | |
| SCHEMBL8138719 | 0.89 | KMT2A (0.40) | KMT2AP2RX7RAB9ANPC1ALDH1A1 | |
| SCHEMBL8138717 | 0.89 | KMT2A (0.40) | KMT2AP2RX7RAB9ANPC1ALDH1A1 | |
| SCHEMBL7759723 | 0.87 | KMT2A (0.53) | KMT2AP2RX7IMPDH2MAPTADCY8 | |
| SCHEMBL7759717 | 0.87 | KMT2A (0.53) | KMT2AP2RX7IMPDH2MAPTADCY8 | |
| SCHEMBL7756420 | 0.79 | KMT2A (0.60) | KMT2AIMPDH2MAPTGAA | |
| SCHEMBL5803661 | 0.79 | KIF11 (0.39) | KMT2ASMN1; SMN2MEN1CETPMAPT | |
| SCHEMBL7756397 | 0.75 | LMNA (0.47) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7753800 | 0.73 | KMT2A (0.57) | KMT2AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10578986 | 0.70 | SMN1; SMN2 (0.41) | KMT2ARAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077933-A1 | SUBSTITUTED GUANIDINES AND DIAMINONITROETHENES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058497-A1 | SUBSTITUTED GUANIDINES AND DIAMINONITROETHENES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |