Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 4/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756711 | 0.85 | SMN1; SMN2 (0.36) | DAOKDM4EALDH1A1HPGDIDH1 | |
| SCHEMBL7756623 | 0.84 | DAO (0.36) | NOX4DAOGRIN1KDM4EALDH1A1 | |
| SCHEMBL7757627 | 0.81 | SMN1; SMN2 (0.36) | DAOKDM4EALDH1A1HPGDIDH1 | |
| SCHEMBL7759953 | 0.80 | NOX4 (0.35) | NOX4DAOGRIN1ALDH1A1MEN1 | |
| SCHEMBL7758785 | 0.80 | NOX4 (0.35) | NOX4GRIN1KDM4EALDH1A1MEN1 | |
| SCHEMBL7753948 | 0.80 | NOX4 (0.35) | NOX4DAOGRIN1ALDH1A1MEN1 | |
| SCHEMBL7758263 | 0.77 | TP53 (0.36) | DAOKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7758268 | 0.77 | TP53 (0.36) | DAOKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7757624 | 0.74 | SMN1; SMN2 (0.39) | KDM4EALDH1A1KMT2AHPGDTSHR | |
| SCHEMBL2107018 | 0.74 | SMN1; SMN2 (0.36) | DAOKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| EP-0736015-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |