Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | TPH1 | P17752 | 1/20 | 0.32 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756711 | 0.88 | SMN1; SMN2 (0.36) | SMN1; SMN2TPH1TPH2DAOHPGD | |
| SCHEMBL7255075 | 0.85 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7753945 | 0.81 | NOX4 (0.35) | DAOHPGDKDM4EALDH1A1IDH1 | |
| SCHEMBL7757624 | 0.80 | SMN1; SMN2 (0.39) | SMN1; SMN2HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL2107018 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2TPH1TPH2DAOHPGD | |
| SCHEMBL7756600 | 0.79 | ALDH1A1 (0.37) | SMN1; SMN2TPH1TPH2DAOHPGD | |
| SCHEMBL7756611 | 0.79 | ALDH1A1 (0.37) | SMN1; SMN2TPH1TPH2DAOHPGD | |
| SCHEMBL7756666 | 0.78 | TPH1 (0.37) | SMN1; SMN2TPH1TPH2DAOHPGD | |
| SCHEMBL7758260 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2ADORA3ADORA2BHPGDKDM4E | |
| SCHEMBL7758222 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2ADORA3ADORA2BHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |