⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456783 | 0.85 | CYP1A1 (0.31) | — | |
| SCHEMBL21268434 | 0.81 | MEN1 (0.40) | — | |
| SCHEMBL27999440 | 0.77 | LOXL2 (0.34) | — | |
| SCHEMBL1369825 | 0.72 | CNR1 (0.41) | — | |
| SCHEMBL1777552 | 0.72 | TSHR (0.31) | — | |
| SCHEMBL27300470 | 0.71 | TSHR (0.39) | — | |
| SCHEMBL206972 | 0.71 | MEN1 (0.33) | — | |
| SCHEMBL206741 | 0.71 | CHRNB2 (0.30) | — | |
| SCHEMBL10771799 | 0.71 | TYR (0.37) | — | |
| SCHEMBL206082 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071660-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE | Novartis AG (CH) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999043644-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ | NOVARTIS AG (CH) | 1999-09-02 | — | — | WO | disclosed |