Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20995435 | 0.94 | HTR2C (0.31) | — | |
| SCHEMBL28299092 | 0.77 | HDAC8 (0.38) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL1778645 | 0.76 | KMO (0.40) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL11270086 | 0.76 | HDAC4 (0.37) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL6568489 | 0.74 | KMO (0.39) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL29125236 | 0.74 | KMO (0.39) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL1636811 | 0.72 | HDAC8 (0.37) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL27008281 | 0.72 | ESR2 (0.35) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL1638138 | 0.71 | HDAC4 (0.34) | HDAC4HDAC2HDAC8ACMSDKMO | |
| SCHEMBL432693 | 0.70 | KMO (0.39) | HDAC4HDAC2HDAC8ACMSDKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071660-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE | Novartis AG (CH) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999043644-A1 | N-SULPHONYL AND N-SULPHINYL PHENYLGLYCINAMIDE___________________ | NOVARTIS AG (CH) | 1999-09-02 | — | — | WO | disclosed |