SCHEMBL7754075

SCHEMBL7754075

O=S(=O)(c1ccc(OCc2ccccc2)cc1)c1ccccc1-c1ccc(O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.56
LMNA P02545 1/20 0.56
PTGS1 P23219 1/20 0.56
SLC6A2 P23975 1/20 0.56
CYP2C19 P33261 1/20 0.56
PTGS2 P35354 1/20 0.56
SLC6A3 Q01959 1/20 0.56
HIF1A Q16665 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
GSTP1 P09211 2/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA5A P35218 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
BCL2L1 Q07817 1/20 0.47
PTGES2 Q9H7Z7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419556 0.85 LMNA (0.73) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL28291811 0.82 CA12 (0.63) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL6899092 0.82 POLB (0.54) BCL2L1GAAMMP13MMP2MMP9
SCHEMBL50524 0.82 CYP1A2 (0.55) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL9661669 0.81 CA12 (0.55) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL11009256 0.81 LMNA (0.67) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL4734126 0.79 MMP2 (0.46) GAAMMP13MMP2MMP9MMP14
SCHEMBL7108878 0.79 CA12 (0.74) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL1790576 0.78 CA12 (0.56) CYP1A2LMNAPTGS1SLC6A2CYP2C19
SCHEMBL7751043 0.78 HTR6 (0.49) CYP1A2LMNAPTGS1SLC6A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0559525-B2 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO LTD (JP) 2001-02-07 EP disclosed
EP-0559525-B1 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO LTD (JP) 1997-11-05 EP disclosed
US-5296441-A Having heat sensitive layer containing monoetherified dihydroxyphenyl sulfone developer, aluminum hydroxide TOMOEGAWA PAPER CO., LTD. (JP) 1994-03-22 US disclosed
EP-0559525-A2 Thermal printing medium and method for preparing the same TOMOEGAWA PAPER CO. LTD. (JP) 1993-09-08 EP disclosed