SCHEMBL9655600

SCHEMBL9655600

COC(=O)[C@@](C)(N)C(=O)[C@H](N)CC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.33
PGD P52209 1/20 0.32
DGAT1 O75907 1/20 0.31
S1PR1 P21453 1/20 0.31
S1PR3 Q99500 1/20 0.31
BHMT Q93088 1/20 0.31
SLC1A1 P43005 1/20 0.31
GFPT1 Q06210 1/20 0.30
LTA4H P09960 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2807597 0.82 GRIK1 (0.35) GRIK1BHMT
SCHEMBL7754149 0.82 GRIK1 (0.35) GRIK1BHMT
SCHEMBL10346841 0.82 BHMT (0.33) GRIK1PGDBHMT
SCHEMBL10346852 0.80 S1PR1 (0.34) S1PR1S1PR3SLC1A1
SCHEMBL18116107 0.76 GRIK1 (0.38) GRIK1BHMTSLC1A1
SCHEMBL12420389 0.76 GRIK1 (0.38) GRIK1BHMTSLC1A1
SCHEMBL15976122 0.74 ALDH1A1 (0.38) GRIK1PGDBHMT
SCHEMBL10632390 0.73 BHMT (0.32) BHMT
SCHEMBL28006164 0.73 KCNN4 (0.47) LTA4H
SCHEMBL6259101 0.71 KMT2A (0.37) S1PR1S1PR3BHMTSLC1A1GFPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0231087-B1 HEPTANOYL-GLU-ASP-ALA-AMINO ACID IMMUNOSTIMULANTS PFIZER INC. (US) 1992-03-25 EP disclosed
EP-0231087-A2 Heptanoyl-glu-asp-ala-amino acid immunostimulants PFIZER INC. (US) 1987-08-05 EP disclosed