Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931358 | 1.00 | LMNA (0.59) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL445888 | 0.98 | LMNA (0.55) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL8812570 | 0.84 | LMNA (0.39) | LMNABLM | |
| SCHEMBL8812227 | 0.84 | LMNA (0.39) | LMNABLM | |
| SCHEMBL14778126 | 0.81 | LMNA (0.48) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL14777945 | 0.81 | LMNA (0.59) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL1827120 | 0.81 | LMNA (0.59) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL8672325 | 0.79 | LMNA (0.93) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL538230 | 0.79 | LMNA (0.93) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL20928 | 0.79 | LMNA (0.93) | LMNABLMPTPN1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670317-B9 | EPOXYCYCLOHEXENEDIONE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0670317-B1 | EPOXYCYCLOHEXENEDIONE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 2000-03-08 | — | — | EP | disclosed |
| US-5565489-A | MICROBIOCIDES, ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0670317-A1 | EPOXYCYCLOHEXENEDIONE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1995-09-06 | — | — | EP | disclosed |