SCHEMBL931358

SCHEMBL931358

CC(C)CCCC(C)CCCC(C)CCCC(C)C[C]=O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
BLM P54132 1/20 0.48
PTPN1 P18031 3/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
ALOX15 P16050 1/20 0.38
KMT2A Q03164 1/20 0.38
PTPN2 P17706 1/20 0.33
CDC25B P30305 1/20 0.33
FNTA P49354 1/20 0.32
PGGT1B P53609 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754183 1.00 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL445888 0.98 LMNA (0.55) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL8812570 0.84 LMNA (0.39) LMNABLM
SCHEMBL8812227 0.84 LMNA (0.39) LMNABLM
SCHEMBL14778126 0.81 LMNA (0.48) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL14777945 0.81 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL1827120 0.81 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL8672325 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL538230 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL20928 0.79 LMNA (0.93) LMNABLMPTPN1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0688555-A2 Hair-growing agent TANABE SEIYAKU CO., LTD. (JP) 1995-12-27 EP claimed
US-12016929-B2 Lipid formulations for delivery of therapeutic agents ARBUTUS BIOPHARMA CORPORATION (CA) 2024-06-25 US disclosed
US-20240182895-A1 NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY ARBUTUS BIOPHARMA CORPORATION (CA) 2024-06-06 US disclosed
US-20240148875-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-05-09 US disclosed
US-20240100166-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS ARBUTUS BIOPHARMA CORPORATION (CA) 2024-03-28 US disclosed
WO-2024026353-A2 ENZYMATIC SYNTHESIS OF MYCOSPORINE-LIKE AMINO ACIDS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-02-01 WO disclosed
US-20240035030-A1 NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY ARBUTUS BIOPHARMA CORPORATION (CA) 2024-02-01 US disclosed
US-11786598-B2 Lipid formulations for delivery of therapeutic agents ARBUTUS BIOPHARMA CORPORATION (CA) 2023-10-17 US disclosed
CN-111481469-B copolymer 宝丽化学工业有限公司 2023-09-19 CN disclosed
CN-111358713-B copolymer 宝丽化学工业有限公司 2023-09-19 CN disclosed
EP-1409551-A4 CHIMERIC CAPSID PROTEINS AND USES THEREOF UAB RESEARCH FOUNDATION (US) 2004-10-13 EP disclosed
WO-2004060912-A2 CHIMERIC CAPSID PROTEINS AND EXPRESSION VECTORS FOR MONOCISTRONIC EXPRESSION OF MULTIPLE GENES UAB RESEARCH FOUNDATION (US) 2004-07-22 WO disclosed
EP-1409551-A2 CHIMERIC CAPSID PROTEINS AND USES THEREOF UAB RESEARCH FOUNDATION (US) 2004-04-21 EP disclosed
WO-2003000855-A2 CHIMERIC CAPSID PROTEINS AND USES THEREOF UAB RESEARCH FOUNDATION (US) 2003-01-03 WO disclosed
EP-0670317-B9 EPOXYCYCLOHEXENEDIONE DERIVATIVE KYOWA HAKKO KOGYO KK (JP) 2001-03-14 EP disclosed
EP-0670317-B1 EPOXYCYCLOHEXENEDIONE DERIVATIVE KYOWA HAKKO KOGYO KK (JP) 2000-03-08 EP disclosed
US-5741816-A CARNITINE COMPOUND TANABE SEIYAKU CO., LTD. (JP) 1998-04-21 US disclosed
US-5565489-A MICROBIOCIDES, ANTITUMOR AGENTS KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-10-15 US disclosed
EP-0688555-A2 Hair-growing agent TANABE SEIYAKU CO., LTD. (JP) 1995-12-27 EP disclosed
EP-0670317-A1 EPOXYCYCLOHEXENEDIONE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 1995-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240100166-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS PNLIP, NPC1L1, CETP LMNA 758/4885BLM 2897/4885PTPN1 2028/4885
US-20240182895-A1 NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY SNRPE, NPC1L1, LIPA LMNA 177/4885BLM 1596/4885PTPN1 1636/4885
US-20240148875-A1 NOVEL LIPID FORMULATIONS FOR DELIVERY OF THERAPEUTIC AGENTS PNLIP, NPC1L1, CETP LMNA 758/4885BLM 2897/4885PTPN1 2028/4885
US-20240035030-A1 NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY SNRPE, NPC1L1, LIPA LMNA 177/4885BLM 1596/4885PTPN1 1636/4885
US-11786598-B2 Lipid formulations for delivery of therapeutic agents CETP, PNLIP, NPC1L1 LMNA 793/4885BLM 3014/4885PTPN1 1747/4885
US-12016929-B2 Lipid formulations for delivery of therapeutic agents CETP, PNLIP, NPC1L1 LMNA 793/4885BLM 3014/4885PTPN1 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.