SCHEMBL445888

SCHEMBL445888

CC(C)CCCC(C)C[C]=O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
BLM P54132 1/20 0.45
PTPN1 P18031 3/20 0.35
MEN1 O00255 1/20 0.35
CYP3A4 P08684 1/20 0.35
ALOX15 P16050 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN2 P17706 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL931358 0.98 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL7754183 0.98 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL8812227 0.81 LMNA (0.39) LMNABLM
SCHEMBL8812570 0.81 LMNA (0.39) LMNABLM
SCHEMBL1410326 0.80
SCHEMBL14778126 0.79 LMNA (0.48) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL8384133 0.78
SCHEMBL14777945 0.78 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL1827120 0.78 LMNA (0.59) LMNABLMPTPN1MEN1CYP3A4
SCHEMBL14836402 0.78 LMNA (0.40) LMNABLMPTPN1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 462 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3109254-B1 CROSSLINKED NUCLEOSIDE AND NUCLEOTIDE UNIV OSAKA (JP) 2018-04-11 EP claimed
WO-2006106528-A1 NOVEL PEPTIDES USEFUL FOR TREATMENT OF ALOPECIA DABUR PHARMA LIMITED (IN) 2006-10-12 WO claimed
US-6828304-B1 Lipid-peptide conjugates containing fatty acids of different sizes, which inhibits the binding of Vasoactive intestinal peptide to its receptor DABUR RESEARCH FOUNDATION (IN) 2004-12-07 US claimed
EP-1409519-A1 LIPID-PEPTIDE CONJUGATES FOR TREATMENT OF CANCER Dabur Research Foundation (IN) 2004-04-21 EP claimed
WO-2002010193-A1 LIPID-PEPTIDE CONJUGATES FOR TREATMENT OF CANCER DABUR RESEARCH FOUNDATION (IN) 2002-02-07 WO claimed
WO-2024135721-A1 METHOD FOR PRODUCING PRODUCTION INTERMEDIATE, PRODUCTION INTERMEDIATE THEREOF, AND METHOD FOR PRODUCING CROSSLINKED ARTIFICIAL NUCLEIC ACID INTERMEDIATE BY USING SAME 田辺三菱製薬株式会社 2024-06-27 WO disclosed
WO-2024101446-A1 MODIFIED NUCLEOSIDE HAVING GUANIDINO STRUCTURE IN BRIDGED PART AND METHOD FOR PRODUCING OLIGONUCLEOTIDE USING SAME ルクサナバイオテク株式会社 2024-05-16 WO disclosed
CN-112513062-B Oligonucleotide-containing small cell lung cancer therapeutic agent 国立大学法人大阪大学 2024-05-10 CN disclosed
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING OSAKA UNIVERSITY (JP) 2024-05-09 US disclosed
CN-117964674-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
CN-117964673-A Bridged artificial nucleic acid ALNA 田边三菱制药株式会社 2024-05-03 CN disclosed
US-11939421-B2 Or relating to curing agents HEXCEL COMPOSITES LIMITED (GB) 2024-03-26 US disclosed
EP-0844000-A1 Use of alpha, omega-diarylalkane derivatives in the treatment and prevention of psychosis SANKYO COMPANY LIMITED (JP) 1998-05-27 EP disclosed
EP-0795326-A1 OCULAR TENSION DEPRESSANT SANKYO COMPANY LIMITED (JP) 1997-09-17 EP disclosed
CN-1157286-A N,N-dimethyl-1-t-butoxycarbonyl-4-phenylpiperidine-4-carboxamide SANKYO CO (JP) 1997-08-20 CN disclosed
EP-0776893-A1 Azaheterocyclic compounds having tachykinin receptor antagonist activity; Nk1 and NK2 SANKYO COMPANY LIMITED (JP) 1997-06-04 EP disclosed
EP-0468497-B1 Peptide-antagonists of bombesin/GRP MERRELL PHARMA INC (US) 1997-05-28 EP disclosed
US-5556864-A TREATMENT OF CIRCULATORY DISEASES AND PSYCHOSIS SANKYO COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0600717-A1 Phenoxyalkylamines, -pyrrolidines and -piperidines for the treatment and prevention of circulatory diseases and psychosis SANKYO COMPANY LIMITED (JP) 1994-06-08 EP disclosed
EP-0468497-A2 Peptide-antagonists of bombesin/GRP MERRELL PHARMACEUTICALS INC. (US) 1992-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240148775-A1 OLIGONUCLEOTIDE FOR INDUCING N-EXON SKIPPING DURING REST MRNA PRECURSOR PROCESSING UPF1, RBM17, NSUN2 LMNA 385/4885BLM 1487/4885PTPN1 1369/4885
US-11939421-B2 Or relating to curing agents FABP4, RARA, ADIPOR1 LMNA 585/4885BLM 190/4885PTPN1 2663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.