SCHEMBL7754237

SCHEMBL7754237

CCCC(=O)OC(=O)NOC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
TSHR P16473 5/20 0.39
CTSD P07339 1/20 0.38
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HDAC3 O15379 4/20 0.34
HDAC1 Q13547 4/20 0.34
HDAC2 Q92769 4/20 0.34
HDAC8 Q9BY41 4/20 0.34
HDAC6 Q9UBN7 1/20 0.34
FFAR3 O14843 3/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
EPHX1 P07099 1/20 0.32
POLB P06746 1/20 0.32
POLA1 P09884 1/20 0.32
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8530891 0.77 ALDH1A1 (0.64) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL28937192 0.77 ALDH1A1 (0.64) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL8529427 0.76 ALDH1A1 (0.61) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL8158 0.75 ALDH1A1 (1.00) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL30568759 0.75 ALDH1A1 (1.00) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL20223657 0.75 ALDH1A1 (0.75) ALDH1A1TSHRCES2CES1HDAC3
SCHEMBL8664791 0.75 ALDH1A1 (0.67) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL473817 0.74
SCHEMBL9556715 0.73 ALDH1A1 (0.94) ALDH1A1TSHRCTSDCES2CES1
SCHEMBL13685 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1068211-A2 PROCESS FOR PURIFICATION OF A CEPHALOSPORIN DERIVATIVE BIOCHEMIE Gesellschaft m.b.H. (AT) 2001-01-17 EP claimed
WO-1999051607-A2 PROCESS FOR PURIFICATION OF A CEPHALOSPORIN DERIVATIVE BIOCHEMIE GESELLSCHAFT MBH (AT) 1999-10-14 WO claimed