Sugi Predict

Sugi Predict / Compounds / (+)-Taxifolin

(+)-Taxifolin

(+)-Taxifolin

SCHEMBL7754279

O=C1c2c(O)cc(O)cc2O[C@H](c2ccc(O)c(O)c2)[C@H]1O.Oc1ccccc1

nearest known ligand 0.90

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 0.90
▸ ALOX15 P16050 4/20 0.90
▸ MAPT P10636 3/20 0.90
▸ HSD17B10 Q99714 3/20 0.90
▸ RECQL P46063 2/20 0.90
▸ SOST Q9BQB4 2/20 0.90
▸ MEN1 O00255 2/20 0.90
▸ KMT2A Q03164 2/20 0.90
▸ KDM4E B2RXH2 2/20 0.90
▸ GAA P10253 2/20 0.90
▸ ALOX12 P18054 2/20 0.90
▸ HIF1A Q16665 2/20 0.90
▸ POLB P06746 1/20 0.90
▸ CYP1A2 P05177 1/20 0.90
▸ NFKB1 P19838 1/20 0.90
▸ MAPK1 P28482 1/20 0.90
▸ SYNJ2 O15056 3/20 0.68
▸ APP P05067 1/20 0.68
▸ XDH P47989 2/20 0.61
▸ IDO1 P14902 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(+)-Taxifolin SCHEMBL30300501 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29368246 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL13241264 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL7628142 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Epitaxifolin SCHEMBL31575455 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL296323 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29367955 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL1707803 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29361519 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
Taxifolin SCHEMBL29358492 0.95 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0866808-B1 METHODS AND APPARATUS FOR THE EXTRACTION OF PHYTOCHEMICALS FROM FIBROUS PLANTS LAREX INC (US) 2001-02-28 — — EP claimed
Send feedback