Taxifolin

Taxifolin

SCHEMBL29358492

O=C1c2c(O)cc(O)cc2OC(c2ccc(O)c(O)c2)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 4/20 1.00
▸ ALOX15 P16050 4/20 1.00
▸ MAPT P10636 3/20 1.00
▸ HSD17B10 Q99714 3/20 1.00
▸ RECQL P46063 2/20 1.00
▸ SOST Q9BQB4 2/20 1.00
▸ MEN1 O00255 2/20 1.00
▸ KMT2A Q03164 2/20 1.00
▸ KDM4E B2RXH2 2/20 1.00
▸ GAA P10253 2/20 1.00
▸ ALOX12 P18054 2/20 1.00
▸ HIF1A Q16665 2/20 1.00
▸ POLB P06746 1/20 1.00
▸ CYP1A2 P05177 1/20 1.00
▸ NFKB1 P19838 1/20 1.00
▸ MAPK1 P28482 1/20 1.00
▸ SYNJ2 O15056 3/20 0.75
▸ APP P05067 1/20 0.75
▸ XDH P47989 2/20 0.67
▸ IDO1 P14902 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taxifolin SCHEMBL29390633 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL30300501 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL30631315 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Epitaxifolin SCHEMBL31575455 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29361519 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL13241264 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL29368246 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL1707803 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL7628142 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL
(+)-Taxifolin SCHEMBL296323 1.00 CYP3A4 (1.00) CYP3A4ALOX15MAPTHSD17B10RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117384217-B Preparation method of composite phosphorus-free water treatment corrosion inhibitor 湖南星君水伯新能源有限公司 2025-05-16 — — CN claimed
CN-117384217-A Preparation method of composite phosphorus-free water treatment corrosion inhibitor 广东天祺环保科技有限公司 2024-01-12 — — CN claimed
WO-2023064318-A1 BIPHASIC COMPOSITIONS COMPRISING ONE OR BOTH OF CARBONATE AND PHOSPHATE Natural Extraction Systems, LLC (US) 2023-04-20 — — WO claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 — — WO claimed
US-20250241889-A1 FORTIFIED WATER LOVANESS LTD (GB) 2025-07-31 — — US disclosed
CN-117384217-B Preparation method of composite phosphorus-free water treatment corrosion inhibitor 湖南星君水伯新能源有限公司 2025-05-16 — — CN disclosed
CN-119424405-A Application of taxifolin in preparation of product for inhibiting expression of uric acid transporter 深圳市第二人民医院(深圳市转化医学研究院) 2025-02-14 — — CN disclosed
CN-119331888-A Polygonatum cyrtonema PcF3H gene and application thereof in promotion of synthesis of dihydroflavonoid compounds and catalysis of naringenin hydroxylation 浙江农林大学 2025-01-21 — — CN disclosed
EP-4484952-A2 OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY The Regents of the University of California (US) 2025-01-01 — — EP disclosed
EP-3661539-B1 OPTIMIZED PEPTIDES FOR TARGETING HUMAN NERVES AND THEIR USE IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY UNIV CALIFORNIA (US) 2024-10-09 — — EP disclosed
EP-4422417-A1 FORTIFIED WATER Lovaness Limited (GB) 2024-09-04 — — EP disclosed
CN-118453453-A Efficient anti-chapping hand cream containing sheep oil and preparation method thereof 严志华 2024-08-09 — — CN disclosed
EP-4041311-A1 METHODS AND SYSTEMS USING PEPTIDES FOR TARGETING AND MAPPING HUMAN NERVES IN IMAGE GUIDED SURGERY, DIAGNOSTICS AND THERAPEUTIC DELIVERY Alume Biosciences, Inc. (US) 2022-08-17 — — EP disclosed
WO-2022123587-A1 A FORMULATION AND/OR COMBINATION TO PREVENT PULMONARY DISEASES INCLUDING SARS-COV-2 GOEL, PAWAN KUMAR (IN) 2022-06-16 — — WO disclosed
WO-2022120177-A1 NERVE TARGETING PEPTIDES AND METHODS OF USE ALUME BIOSCIENCES, INC. (US) 2022-06-09 — — WO disclosed
US-11292758-B2 Compounds and methods for delivery of prostacyclin analogs UNITED THERAPEUTICS CORPORATION (US) 2022-04-05 — — US disclosed
CN-111218406-B Mucor circinelloides MF-8 and application thereof in improving content of taxifolin in rhizoma smilacis glabrae 浙江工业大学 2022-03-15 — — CN disclosed
CN-113214210-B Preparation method of dihydroquercetin 合肥立方制药股份有限公司 2022-03-04 — — CN disclosed
CN-114031656-A Medicine for treating urinary calculus related diseases and preparation method thereof 张弘 2022-02-11 — — CN disclosed
US-20220024845-A1 COMPOUNDS AND METHODS FOR DELIVERY OF PROSTACYCLIN ANALOGS UNITED THERAPEUTICS CORPORATION (US) 2022-01-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220024845-A1 COMPOUNDS AND METHODS FOR DELIVERY OF PROSTACYCLIN ANALOGS PTGIR, PTGIS, PGF CYP3A4 3256/4885ALOX15 54/4885MAPT 4705/4885
US-11292758-B2 Compounds and methods for delivery of prostacyclin analogs PTGIR, PTGIS, PGF CYP3A4 2603/4885ALOX15 46/4885MAPT 4720/4885
US-20250241889-A1 FORTIFIED WATER AQP1, AQP3, ADH1B CYP3A4 1756/4885ALOX15 1704/4885MAPT 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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