Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754465 | 0.86 | MRGPRX1 (0.34) | NR3C1ARDHODHBRAF | |
| SCHEMBL7753846 | 0.81 | BRD4 (0.35) | NR3C1ARBRD4BRAF | |
| SCHEMBL39236 | 0.78 | DHODH (0.43) | DHODH | |
| SCHEMBL4677597 | 0.77 | PPOX (0.33) | NR3C1ARBRD4BRAF | |
| SCHEMBL6310984 | 0.77 | DHODH (0.38) | DHODH | |
| SCHEMBL4677562 | 0.73 | PPOX (0.43) | NR3C1AR | |
| SCHEMBL6309209 | 0.72 | DHODH (0.43) | DHODH | |
| SCHEMBL6695602 | 0.72 | BRD4 (0.32) | BRD4 | |
| SCHEMBL6315602 | 0.71 | DHODH (0.38) | DHODH | |
| SCHEMBL27549447 | 0.71 | PGR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1305466-A | Substituted phenyl pyridazinones | BAYER AG (DE) | 2001-07-25 | — | — | CN | disclosed |
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |