Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.34 |
| ▸ | DHODH | Q02127 | 5/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 2/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754463 | 0.86 | NR3C1 (0.33) | DHODHNR3C1ARBRAF | |
| SCHEMBL7753846 | 0.80 | BRD4 (0.35) | NR3C1ARBRAF | |
| SCHEMBL8517457 | 0.79 | DHODH (0.47) | DHODH | |
| SCHEMBL8227965 | 0.77 | DHODH (0.40) | DHODH | |
| SCHEMBL4677597 | 0.76 | PPOX (0.33) | NR3C1ARBRAF | |
| SCHEMBL4677562 | 0.73 | PPOX (0.43) | NR3C1AR | |
| SCHEMBL7253342 | 0.70 | SCN9A (0.44) | — | |
| SCHEMBL4679914 | 0.69 | BAZ2B (0.40) | BRAF | |
| SCHEMBL31448215 | 0.69 | NOTUM (0.37) | CCR1 | |
| SCHEMBL4681846 | 0.69 | NOTUM (0.37) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |