Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 13/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754621 | 0.93 | ITGB3 (0.47) | ITGB3ITGA2BPSMB8PSMB5USP2 | |
| SCHEMBL7752387 | 0.87 | MMP2 (0.44) | ITGB3ITGA2BPSMB8 | |
| SCHEMBL7748774 | 0.85 | ITGB3 (0.59) | ITGB3ITGA2BUSP2ITGAV | |
| SCHEMBL27450344 | 0.82 | USP2 (0.41) | ITGB3ITGA2BPSMB8PSMB5USP2 | |
| SCHEMBL7753617 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BPSMB8PSMB5USP2 | |
| SCHEMBL7752664 | 0.80 | SYK (0.47) | ITGB3ITGA2BPSMB8ITGAV | |
| SCHEMBL7753678 | 0.80 | ITGB3 (0.60) | ITGB3ITGA2BITGAV | |
| SCHEMBL7752666 | 0.80 | MMP2 (0.45) | ITGB3ITGA2BPSMB8ITGAV | |
| SCHEMBL7754751 | 0.79 | MMP2 (0.42) | ITGB3ITGA2BPSMB8PSMB5 | |
| SCHEMBL8902514 | 0.79 | ITGAV (0.52) | ITGB3ITGA2BPSMB8PSMB5USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725059-B1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMA (JP) | 2001-01-17 | — | — | EP | disclosed |
| US-6048854-A | ANTICOAGULANTS; ANTICANCER AGENT; WOUND HEALING AGENTS;BONE DISORDERS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| US-5707994-A | USEFUL AS A PLATELET AGGREGATION INHIBITOR, CANCER METASTASIS INHIBITOR, WOUND HEALING AGENT OR A BONE RESORPTION INHIBITOR | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0725059-A1 | 2,3-DIAMINOPROPIONIC ACID DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-08-07 | — | — | EP | disclosed |