Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 9/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | ACR | P10323 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7754676 | 1.00 | TACR3 (0.36) | TACR3NPC1LMNACYP1A2CYP3A4 | |
| SCHEMBL7757063 | 0.94 | CHRNA3 (0.37) | TACR3NPC1LMNACYP1A2CYP3A4 | |
| SCHEMBL7757065 | 0.94 | CHRNA3 (0.37) | TACR3NPC1LMNACYP1A2CYP3A4 | |
| SCHEMBL7757050 | 0.88 | LMNA (0.37) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7757049 | 0.88 | LMNA (0.37) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7755753 | 0.86 | ALDH1A1 (0.36) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7755752 | 0.86 | ALDH1A1 (0.36) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7755692 | 0.86 | NPC1 (0.40) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7755688 | 0.86 | NPC1 (0.40) | NPC1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7755732 | 0.84 | LMNA (0.34) | NPC1LMNACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708107-B1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHINETSU CHEMICAL CO (JP) | 2001-02-28 | — | — | EP | disclosed |
| US-5624601-A | Silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0708107-A1 | Novel silacyclohexane compounds, a liquid crystal composition comprising the same and a liquid crystal device comprising the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-24 | — | — | EP | disclosed |