Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774518 | 0.84 | MAOB (0.36) | PGK1MAOBCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6729897 | 0.83 | TRPV4 (0.36) | PGK1MAOBCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL6736259 | 0.79 | PGK1 (0.44) | SRCPGK1MAOBSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6831304 | 0.78 | PGK1 (0.43) | SRCPGK1MAOBSLC6A2SLC6A4 | |
| SCHEMBL6505718 | 0.77 | ALDH1A1 (0.45) | SRCEGFRERBB2 | |
| SCHEMBL6497939 | 0.74 | CYP11B1 (0.39) | CYP2D6SLC6A2SLC6A4NOS2EGFR | |
| SCHEMBL3628472 | 0.72 | TRPV4 (0.50) | TRPV4 | |
| SCHEMBL2081398 | 0.69 | TRPV4 (0.45) | HPGDTRPV4LMNA | |
| SCHEMBL14030008 | 0.68 | TRPV4 (0.37) | TRPV4TSHR | |
| SCHEMBL28398213 | 0.68 | MEN1 (0.40) | MAOBHPGDTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070055-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | Bayer Aktiengesellschaft (DE) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999052878-A1 | SUBSTITUTED PHENYL PYRIDAZINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-10-21 | — | — | WO | disclosed |