SCHEMBL7754819

SCHEMBL7754819

CN1CCOCC1c1nc[nH]n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27866205 0.76 GSK3B (0.32)
Hydrochloric Acid SCHEMBL21179443 0.74 GSK3B (0.32)
SCHEMBL30557777 0.70 MAPK1 (0.37)
Hydrochloric Acid SCHEMBL30024640 0.69 MAPK1 (0.36)
SCHEMBL16795107 0.66 PIK3C3 (0.43)
SCHEMBL16130585 0.65 CHRNB2 (0.55)
SCHEMBL16130557 0.65 CHRNB2 (0.55)
SCHEMBL2606087 0.65 CHRNB2 (0.55)
SCHEMBL13634727 0.64 SMN1; SMN2 (0.44)
SCHEMBL7759048 0.64 HDAC1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1085875-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING PSYCHIATRIC DISORDERS MERCK SHARP &amp; DOHME LTD. (GB) 2001-03-28 EP claimed
WO-1999064010-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING PSYCHIATRIC DISORDERS MERCK SHARP & DOHME LIMITED (GB) 1999-12-16 WO claimed
EP-1085875-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING PSYCHIATRIC DISORDERS MERCK SHARP &amp; DOHME LTD. (GB) 2001-03-28 EP disclosed
EP-1085874-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING SEXUAL DYSFUNCTIONS MERCK SHARP &amp; DOHME LTD. (GB) 2001-03-28 EP disclosed
WO-1999064010-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING PSYCHIATRIC DISORDERS MERCK SHARP & DOHME LIMITED (GB) 1999-12-16 WO disclosed
WO-1999064008-A1 USE OF A NK-1 RECEPTOR ANTAGONIST FOR TREATING SEXUAL DYSFUNCTIONS MERCK SHARP & DOHME LIMITED (GB) 1999-12-16 WO disclosed