Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926874 | 0.81 | SLC1A3 (0.56) | ESR1LMNACYP1A2PGRCHRM2 | |
| SCHEMBL3929909 | 0.81 | POLB (0.46) | ESR1LMNACYP1A2PGRCHRM2 | |
| SCHEMBL3923620 | 0.80 | MMP2 (0.56) | ADAMTS4MEN1KMT2AL3MBTL1 | |
| SCHEMBL3936338 | 0.80 | MMP2 (0.56) | CYP1A2CYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL3924479 | 0.79 | ADAMTS4 (0.63) | ADAMTS4 | |
| SCHEMBL3927814 | 0.79 | NR3C1 (0.57) | PGR | |
| SCHEMBL3935028 | 0.79 | SLC1A3 (0.59) | LMNAMAPTADAMTS4HSD17B10MEN1 | |
| SCHEMBL3928965 | 0.78 | SLC1A3 (0.40) | ESR1LMNACYP1A2PGRCHRM2 | |
| SCHEMBL5580175 | 0.77 | ESR1 (0.49) | ESR1LMNACYP1A2PGRCHRM2 | |
| SCHEMBL3927049 | 0.75 | SLC1A2 (0.51) | ESR1LMNACYP1A2PGRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1076557-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-02-21 | — | — | EP | claimed |
| WO-1999055324-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-04 | — | — | WO | claimed |
| EP-1076557-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-02-21 | — | — | EP | disclosed |
| WO-1999055324-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-11-04 | — | — | WO | disclosed |